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Claudio Trapella Selected Research

Chronic Pain

1/2017A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism.

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Claudio Trapella Research Topics

Disease

5Pain (Aches)
04/2024 - 06/2006
4Hypothermia
09/2020 - 06/2016
4Parkinsonian Disorders (Parkinsonism)
03/2011 - 02/2007
4Tics (Tic)
02/2010 - 06/2006
3Seizures (Absence Seizure)
04/2024 - 06/2016
3Reperfusion Injury
11/2023 - 01/2018
3Neoplasms (Cancer)
10/2019 - 11/2010
2Inflammation (Inflammations)
09/2022 - 01/2020
2Cystic Fibrosis (Mucoviscidosis)
02/2022 - 01/2020
2Substance-Related Disorders (Drug Abuse)
01/2021 - 03/2017
2Abnormal Reflex (Hyperreflexia)
10/2016 - 06/2016
2Catalepsy
10/2016 - 06/2016
2Neurodegenerative Diseases (Neurodegenerative Disease)
04/2014 - 11/2010
2Hypokinesia (Bradykinesia)
12/2008 - 06/2008
1Ischemia
11/2023
1Infections
01/2022
1Dry Eye Syndromes (Dry Eye Syndrome)
12/2021
1Corneal Injuries
12/2021
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
10/2021
1Gallstones (Gallstone)
10/2021
1Cough
01/2021
1Pruritus (Itching)
01/2021
1Respiratory Insufficiency (Respiratory Failure)
01/2021
1Sickle Cell Anemia (Hemoglobin S Disease)
10/2020
1Thalassemia
10/2020
1Hemoglobinopathies
10/2020
1Pseudomonas Infections
01/2020
1Pneumonia (Pneumonitis)
01/2020
1Myocardial Infarction
01/2018
1Mental Disorders (Mental Disorder)
03/2017
1Hyperthermia
01/2017
1Chronic Pain
01/2017
1Breast Neoplasms (Breast Cancer)
11/2015
1Hypersensitivity (Allergy)
11/2015
1Neuralgia (Stump Neuralgia)
11/2015
1Virus Diseases (Viral Diseases)
10/2015

Drug/Important Bio-Agent (IBA)

8NociceptinIBA
01/2021 - 02/2007
5Opioid Receptors (Opioid Receptor)IBA
01/2021 - 06/2006
4LigandsIBA
11/2023 - 02/2010
3Analgesics (Analgesic Drugs)IBA
12/2021 - 08/2016
36'- fluoro- 4',9'- dihydro- N,N- dimethyl- 4- phenylspiro(cyclohexane- 1,1'(3'H)- pyrano(3,4- b)indol)- 4- amineIBA
01/2021 - 08/2016
3Proteins (Proteins, Gene)FDA Link
01/2020 - 11/2010
2Peptides (Polypeptides)IBA
04/2024 - 07/2008
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2018 - 06/2008
2Opioid Peptides (Opioid Peptide)IBA
11/2015 - 12/2008
2Proteasome Endopeptidase Complex (Proteasome)IBA
11/2010 - 07/2008
2Opioid Analgesics (Opioids)IBA
02/2010 - 06/2006
2Oxidopamine (6 Hydroxydopamine)IBA
12/2008 - 02/2007
2Levodopa (L Dopa)FDA LinkGeneric
12/2008 - 02/2007
2J 113397IBA
06/2008 - 02/2007
1Therapeutic UsesIBA
04/2024
1Formaldehyde (Formol)FDA Link
04/2024
1OligomycinsIBA
11/2023
1oligomycin AIBA
03/2023
1AntioxidantsIBA
09/2022
1acetoacetic acid (acetoacetate)IBA
09/2022
1Ketone BodiesIBA
09/2022
1ProdrugsIBA
02/2022
1Ibuprofen (Motrin)FDA LinkGeneric
02/2022
1Interleukin-8 (Interleukin 8)IBA
02/2022
1Viral DNAIBA
01/2022
1Ophthalmic Solutions (Eye Drops)IBA
12/2021
1Messenger RNA (mRNA)IBA
12/2021
1Biomarkers (Surrogate Marker)IBA
12/2021
1Bile Acids and Salts (Bile Acids)IBA
10/2021
1CholesterolIBA
10/2021
1Ursodeoxycholic Acid (Urso)FDA LinkGeneric
10/2021
1Antitussive Agents (Antitussives)FDA Link
01/2021
1Nociceptin ReceptorIBA
01/2021
1NeuropeptidesIBA
01/2021
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2021
1GlobinsIBA
10/2020
1Small Molecule LibrariesIBA
10/2020
1Fetal Hemoglobin (Hemoglobin F)IBA
10/2020
11-(2-thienyl)-2-(methylamino)propaneIBA
09/2020
1Protein Tyrosine PhosphatasesIBA
01/2020
1R-SNARE Proteins (Vesicle-Associated Membrane Protein)IBA
01/2020
1CalciumIBA
01/2020
1mitochondrial calcium uniporterIBA
01/2020
1IgA receptor (protein B)IBA
01/2020
1nonaneIBA
10/2019
1Dichloroacetic AcidIBA
10/2019
1IonsIBA
10/2019
1MetalsIBA
10/2019
1Adenosine Triphosphate (ATP)IBA
01/2018
1decaneIBA
01/2018
1Nootropic Agents (Nootropics)IBA
03/2017
1Anti-Anxiety Agents (Anxiolytics)IBA
03/2017
11-(1- pentyl- 1H- indol- 3- yl)- 2- (2- methoxyphenyl)ethanoneIBA
06/2016
1JWH-073IBA
06/2016
1Oxaliplatin (Eloxatin)FDA LinkGeneric
11/2015
1Morphine (MS Contin)FDA LinkGeneric
11/2015
1Paclitaxel (Taxol)FDA LinkGeneric
11/2015
1Nphe(1)- (pF)Phe(4)- Aib(7)- Arg(14)- Lys(15)- nociceptin-amideIBA
11/2015
1HLA-G Antigens (HLA G)IBA
10/2015

Therapy/Procedure

3Analgesia
09/2020 - 01/2017
2Therapeutics
11/2023 - 02/2007
2Drug Therapy (Chemotherapy)
11/2015 - 11/2010
1Induced Hypothermia
10/2016
1Aftercare (After-Treatment)
06/2014